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JWH-018 is more powerful than THC or tetrahydrocannabinol, The crucial element Energetic component in cannabis. A little dose is adequate to induce an intoxicating effect. JWH-018 binds the CB1 receptor 4 times a lot more tightly as well as CB2 receptor ten situations a lot more tightly than THC.Indeed, synthetic cannabinoids is usually addictive.